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A rare case of Crigler-Najjar syndrome type II with pregnancy

Rachna Chaudhary, Amit Maheshwari, Deepmala, Virendra Tapparwal.

Abstract
Crigler-Najjar syndrome (CNS) has been rarely described during pregnancy with only few case reports available in literature, CNS is expressed in two forms, CNS type I and CNS type II; Type I CNS results in severe unconjugated hyperbilirubinemia and neurological impairment in newborn and is fatal. Type II CNS results in milder unconjugated hyperbilirubinemia responding to Phenobarbital treatment with better outcome.

Key words: Pregnancy, Hyperbilirubinemia



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