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Cukurova Med J. 2014; 39(3): 546-549

Five Years Experience In Surgical Treatment of Wilms Tumor

Önder Özden, Ender Fakıoğlu, Murat Alkan, Hilmi Serdar İskit, Recep Tuncer, Hasan Okur, Serhan Küpeli, Şeyda Erdoğan, Süreyya Soyupak, Ünal Zorludemir.

Purpose: To evaluate the treatment results of the patients operated with diagnosis of Wilms’ tumor .
Materials and Methods: The records of patients operated for Wilms’ tumor in 2008-2012 were evaluated retrospectively. Sex, age, additional anomalies, tumor stages, preoperative biopsy and chemotherapy history, histopathological features, preoperative tumor rupture, complications and survival rates were reviewed
Results: Male/Female ratio of total 31 patients operated due to Wilms’ tumor was 0.7 and mean age was 3.1 years (6 months – 11 years). Five of the patients had additional congenital anomalies. Thirteen patients had stage I tumor, 6 had stage II, 6 had stage III, 3 had stage IV and 3 had stage V. Eleven of the patients underwent immediate nephrouretectomy as a first intervention, eleven patients went through delayed nephrouretectomy after neoadjuvant chemotherapy without biopsy, eight patients were diagnosed via biopsy and underwent delayed nephrectomy after neoadjuvant chemotherapy. One of the patients went through immediate nephrouretectomy with biopsy. The histopathologic examination of 68,9% of the patients reported as triphasic Wilms’ tumor. Three patients had positive surgical margins. Peroperative spillage was experienced in two patients. Two patients had postoperative complications (pneumonia and meningitis) and three patients had tumor relapses. Mean follow-up period was 2.9 years (1-6 years) and no mortality was observed.
Conclusion: Increased surgical experience, development of radiologic imaging techniques and chemotherapeutic reduction of tumor size make treatment of Wilms’ tumor easier and increase the survival rate.

Key words: Wilms\' tumor, children, surgical treatment

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