Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access


IJHSR. 2014; 4(2): 46-52

Altered Circadian Secretion of Salivary Cortisol during Night Shift.

Anjum B, Verma N S, Tiwari S, Fatima G, Naz Q, Bhardwaj S, Singh P, Mishra S, Singh R, Mahdi A A.

Background: Rotating night shift disrupts the circadian rhythms and has been associated with physiological stress, general fatigue, sleep disturbances and cardiovascular diseases. Alterations in the sleep pattern leads to increased cortisol and decreased melatonin which might be associated physiological stress and cardiovascular diseases.
Objectives: The objective of the present study was to investigate circadian secretion of salivary cortisol in rotating night shift nursing professionals.
Methods: 62 healthy nursing professionals of both genders performing day and night shifts duties were recruited. Each study subject had a monthly scheduled of regular 9 night shifts (12 hours night shift, from 20:00 to 08:00) followed by remaining 17-18 day shifts (6 hours day shift, from 08:00 to 14:00) with a total of 4 days off in between. Saliva samples were collected at around 8 hours interval while they were performing night duties and repeated when they were assigned day duties. Salivary cortisol level was estimated by the ELISA (Competitive) method.
Results: Significant difference was found in night cortisol among night (4.34 3.37) vs day shift (2.70 2.32), (p

Key words: Rotating night shift; circadian rhythm; salivary cortisol.

Share this Article

Journal of Molecular Pathophysiology


ScopeMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Suggest a Journal
Publisher Login
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.
Scopemed Buttons