Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

Original Article



The effect of obesity on total antioxidant/oxidant status and oxidative stress index in patients with chronic periodontitis

Oguz Kose, Varol Canakci, Cenk Fatih Canakci, Abdulkadir Yildirim, Eda Kermen, Taner Arabaci, Adem Gungor.

Abstract
Objective: The aim of this study was to evaluate the possible effects of obesity on the local and systemic total oxidant status (TOS), total antioxidant status (TAS), and oxidative stress index (OSI) in patients with chronic periodontitis.
Methods: The study included 88 subjects assigned to four groups of 22 subjects each, as follows: O+CP+ (patients with obesity and periodontitis); O P+ (patients with normal weight and periodontitis); O+P (periodontally healthy patients with obesity); and the control group consisting of periodontally healthy patients with normal weight (O P ). Serum and salivary samples were obtained a week before the recording of clinical periodontal parameters. Local and systemic TOS and TAS levels were determined biochemically.
Results: TOS and OSI levels were higher and TAS levels were lower in the serum and saliva of the obese individuals with periodontitis. However, TAS, TOS and OSI levels were found to be comparable in patients with obesity or periodontitis.
Conclusion: Our results suggest that obesity might play a destruction provoking role in the pathogenesis of periodontitis by negatively affecting oxidative parameters.

Key words: Obesity; Oxidative stress; Periodontitis; Total antioxidant status



Share this Article


Advertisement
American Journal of Research in Medical Sciences

SUBMIT YOUR ARTICLE NOW


ScopeMed.com
ScopeMed Home
Follow ScopeMed on Twitter
BiblioCAM
Author Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.
Scopemed Buttons