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Osmotic Release Oral System Methylphenidate is more effective than Immediate Release Methylphenidate: a retrospective chart review in Turkish children with attention deficit hyperactivity disorder.

Ülkü Akyol Ardiç, Eyüp Sabri Ercan, Elif Ercan, Deniz Yüce, Bürge Kabukçu Başay.

Objective: The aim of this study was to evaluate the efficacy and safety of osmotic release oral system methylphenidate (OROS-MPH) compared with immediate release methylphenidate (IR-MPH) in Turkish children with attention deficit hyperactivity disorder (ADHD).
Method: The medical records of primary school-aged children, who were first-time referrals to the outpatient clinic, were reviewed; 67 children receiving OROS-MPH and 47 children receiving IR-MPH were recruited for the study. A total of 114 children receiving treatment for ADHD were evaluated over 8 weeks.
Results: The total Turgay DSM-IV Based Child and Adolescent Behavior Disorders Screening and Rating Scale scores from both the parent and teacher forms decreased significantly in both groups over 8 weeks (p

Key words: Attention Deficit Hyperactivity Disorder, methylphenidate, children

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Journal of Molecular Pathophysiology


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