Primary breast lymphoma (PBL) is a rare disease which comprises of 0.04-1.1% of all the malignant tumors of the breast. We report a case of Primary Non-Hodgkin lymphoma (NHL) of the breast in a 50yr old female who presented with painless lump in the right breast. Fine needle aspiration cytology (FNAC) suggested malignancy. This was followed by biopsy and mastectomy which diagnosed the case as Primary NHL of the breast. This was confirmed by immunohistochemistry (IHC) as Diffuse Large B cell lymphoma (DLBCL) with immunoblastic features. Investigations to rule out any other site of lymphoma proved it to be primary NHL.
Primary Non Hodgkin lymphoma, Fine Needle Aspiration Cytology, Diffuse Large B-Cell lymphoma, Immunohistochemistry