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IJHSR. 2013; 3(2): 30-37


Link between Psychiatric and Autoimmune Thyroid Disorder.

Mohammad Maqbool Dar, Sheikh Shoib, Haamid Bashir, Mohammad Hayat Bhat, Waseem Hassan Ahangar.

Abstract
Background: The autoimmune disorders and psychiatric diseases seem to be linked in a same aberrancy in the immune-endocrine system. An association between mood disorder and thyroid immunity had been demonstrated in community samples, psychiatric patients as well as primary care patients, so psychiatric evaluation in thyroid autoimmunity was planned.
Objective: The aim of the study was to assess the pattern of psychiatric morbidity in autoimmune disorders.
Methodology: We conducted a cross-sectional study in SMHS Government medical college associated Hospital. We selected every alternate autoimmune thyroid patients by Stratified random sampling attending to the endocrinological OPD. General description, demographic data and psychiatric history were recorded using the semi structured interview scale. Selected patients were subjected to Mini International Neuropsychiatric Interview –Plus (MINI - Plus) for evaluation of symptoms and diagnosis. A control group (n = 49) was selected amongst the patients and the same instruments were applied. Data was analyzed and associations were tested using the Chi square test. The results expressed as percentages.
Results: Out of total 49 subjects 18 were males (36.7%), and 31 females (63.26%). Most of cases belong to 25 -40 year age group (46.93%) followed by age group 41 – 50 years (26.5%) and 32.6 % were married and 63.2% were unmarried. 65.5 % of patients had significant psychiatric morbidity. Only 34.69 % of the control group had psychiatric problems (p = 0.044) highly significant. Depressive disorder (28.6%) was the most common presentation, followed by panic disorder (8.2%).
Conclusion: The increased frequency of psychiatric morbidity among the thyroid raises the need for early diagnosis and prompt treatment.

Key words: Autoimmune thyroid disorder, morbidity



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