Cigarette smoking is one of the prime causes of increased mortality and morbidity in developed countries and the prevalence is increasing in developing world. Poisoning the body with carbon monoxide causes physical illness like emphysema, chronic bronchitis, arterial damage. The nicotine levels in plasma correspond to blood cortisol levels. The purpose of this study was to compare the serum cortisol and the degree of perceived stress among smokers and non smokers. This study included 30 students (15 smokers, 15 non smokers) from 1st year and similar group was chosen from 3rd year medical students. Body mass index, waist circumference and resting blood pressure were assessed. Perceived stress was assessed using Presumptive stressful life event scale. Serum cortisol level was estimated by Electrochemiluminescence immunoassay on a HITACHI 917 analyzer. The data was statistically analyzed using students t test and chi-square test. P value
Cigarette smoking, Serum cortisol, Electrochemiluminescence immunoassay, Hypothalamo-Pitutary-Adrenal Axis.