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IJHSR. 2014; 4(9): 69-74

Multidrug Resistant Gram Negative Bacilli in Clinical Isolates in a Tertiary Care Hospital.

Satyajeet K. Pawar, Ravindra V.Shinde, H.V. Patil, S.R.Patil, G.S.Karande, S.T.Mohite.

Introduction: Antibiotic resistance is emerging as major health related issue in last few years. All over world there have been growing epidemics of infections due to gram negative bacteria resistant to many classes of antibiotics. New terminologies like multidrug resistant (MDR) and pandrug resistant (PDR) bacteria have been established.
Aims: 1) To find out incidence of Multidrug resistant gram negative bacilli in clinical isolates. 2) To find out sensitivity profile for antibiotic groups. 3) To find out incidence of Pan drug resistant gram negative bacilli.
Materials and Methods: Clinical specimens received in Microbiology department over a period of 6 months were included in the study. Bacterial identification was done by standard methodology. Isolated organisms sensitivity testing for antibiotic groups like aminoglycosides, fluroquinolones, cephalosporins, penicillins, phenicols, tetracyclines, folate inhibitors was done by Kirby - Baur Disk diffusion method.
Results: Of 772 gram negative isolates, 62.2 % were MDR gram negative bacilli and 26.1 % were PDR gram negative bacilli
Conclusion: There was alarming drug resistance level. There should be judicious use of antibiotics and Antibiotic Stewardship Program may help the worsening condition of drug resistance.

Key words: Gram Negative Bacilli, Multidrug Resistant (MDR), Pandrug Resistant (PDR)

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Journal of Molecular Pathophysiology


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