Central giant cell granuloma is a nonneoplastic intraosseous lesion, and constitutes common nonodontogenic pathology in the jaws. Although “central” giant cell granulomas usually occur in the bone, some rare cases behave as extremely aggressive with perforation of the cortices and present themselves as exophytic growth leading to clinical misdiagnosis. Here, we are reporting a very rare case of “aggressive” central giant cell granuloma arising from the anterior mandible as an exophytic growth which resembled a wide variety of conditions leading to misdiagnosis. So, here is an attempt to enlighten the knowledge about such lesions and include them in the differential diagnosis list.
Aggressive giant cell, granuloma