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Imprudent use of proton pump inhibitors in current practice

Manali Mangesh Mahajan, Sujata Dudhgaonkar, Swapnil Narayan Deshmukh.

In a developing country like India, where over 500 branded formulations of PPI are available, probability of misuse and abuse increases exponentially. Although a safe and very effective class of pharmaceutical agent, PPIs should be used only when there is documented evidence of a GI disorder that cannot be treated with an H2-receptor antagonist, and where a PPI use is clinically justified. Increased clinician awareness on appropriate PPI prescription will lead to better patient outcome at lower cost.

Key words: Gastroprotective agents, Acid peptic disease, Proton pump inhitors

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