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Effect of aging on WBC count and Platelet count

Maulik S. Padalia, R, S. Trivedi, Keshur Karmur, Bhavin Kansagara, Priti Bhanderi.

Abstract
Background: Aging is not a disease but due to biochemical changes in tissue it increase risk for development of disease. It also affects the blood cells count.

Aims: To determine the changes of aging as early as possible and thereby extending life span.

Material and Methods: The prospective cross sectional study was conducted in the Physiology Department in collaboration with Pathology Department at M. P Shah Govt. Medical College, Jamnagar, Gujarat with sample size of 103 in the age group of 20 to 89 years. Out of these, 53 were males and 50 were females. Blood parameters were measured by automated cell counter.

Result: Our result showed that Platelet count decrease significantly in males after sixth decade. In females, the changes were not significant in most of the blood parameters.

Conclusion: Poor nutrition resulting in vitamin B12 and folic acid deficiency in old age might be the cause of early hematological changes and early aging. Non significant changes of blood parameters in females might have some hormonal correlation. Further study with large sample size may reveal more information.

Key words: Blood cells, aging, Hematological parameters



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