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IJHSR. 2015; 5(2): 418-423

Multiple Midlines Intracranial Germinomas: A Case Report and Review of Literature.

Deb Kumar Boruah, Vinay Kumar Doddaballapur Prasanna Kumar, Arjun Prakash, Skandesh B M.

Germinomas are the most common intracranial germ cell tumors commonly found in children and adolescents with a mean age of 8-10 years. Intracranial germinomas occur with a strong male predominance and approximately 95% are found in the midline in the pineal (65%) and suprasellar (about 25%) regions. We report a case of multiple midline intracranial germinomas in the pineal, suprasellar and optico-chiasmatic regions presenting in a patient aged 20 years. Synchronous lesions in suprasellar and pineal regions are very rare and are almost exclusively germinomas accounting for 2-13% of all intracranial germ cell tumors and can be concluded that no further evaluation is necessary before initiating therapy in a case of synchronous pineal and sellar lesions with typical neuroimaging features and normal serum oncoproteins.

Key words: germinoma, multiple midline tumors, oncoproteins, CSF (cerebral spinal fluid), MRI (Magnetic Resonance Imaging).

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