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IJHSR. 2015; 5(2): 151-156


Human Immunodeficiency Virus (HIV) and Hepatitis B Infections among Pregnant Women in Ekiti, South-West Nigeria.

Thompson Joseph Akinbolaji, Christopher Oluwasegun Adeosun, Adegboyega Agbaje, Peter Ojo Famoni, Tolulope Adekoya-Benson, Omoniyi Ajala, Omobolanle Olatimehin, Haleem Olujuwon Ibraheem.

Abstract
Human Immunodeficiency Virus (HIV) and hepatitis B (HBV) infections are the most common infections among pregnant women and are of global concern to the public health. This study was therefore carried out to know the prevalence of HIV and HBV infections among pregnant women in Ekiti, South-West, Nigeria. Pregnant women who attended ante-natal clinic at Ekiti State University Teaching Hospital, Ado-Ekiti, between January to November, 2014 were recruited into this study after obtaining their consent. 4ml of blood was aseptically collected from each subject into plain bottles. Each blood sample was allowed to stand for one hour at room temperature (25) for clotting and clot retraction to take place. It was spun and sera separated into plain khan tubes labeled appropriately and the sera were screened for the presence of antibody to HIV and HBV using One-Stage Rapid Test kit (Determine, Uni-gold and Stat-pak with serial algorithm used for HIV and DiaSpot Diagnostics for HBV) and they were later confirmed using enzyme linked immuno sorbent assay (ELISA) (Stat Fax Awareness, England). Out of the 1433 pregnant women recruited, 74(5.16%) were positive to HIV and 52(3.63%) positive to HBV while 10(0.70%) are co-infected with HIV and HBV with highest prevalence in the age group 31-40 years. This study showed high prevalence of both HIV and HBV infections with HIV higher than HBV. It is therefore advisable to always screen pregnant women for these infections at their first visit to ante-natal clinic so as to be able to give adequate management to those having the infections in order to prevent mother to child transmission of these infections.

Key words: prevalence, HIV, HBV, pregnant women



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