This was prospective, randomized, non blinded study carried out in department of Anaesthesiology and Critical Care, Meenakshi Mission Hospital and Research Centre, Madurai, Tamil Nadu on 120 ASA- I patients, undergoing elective laparoscopic surgery. In our study, at intubation, the mean pulse rate was above the baseline value in both groups with 0.65% rise in Group S and 5% rise in Group D. In sevoflurane group there was downward trend in pulse rate from baseline value starting from incision and continued till 45 minutes after intubation and after 45 minutes there was increase in heart rate in sevoflurane group. Maximum fall in pulse rate in group S was at 15 minutes (6.8%). In desflurane group there was upward trend in pulse rate from baseline value starting from incision till the end of surgery. Maximum increase in pulse rate in group D was at 60 minutes (14.7%).Pulse rate was satisfactorily maintained within ± 20% of baseline values in both groups. At intubation, the mean arterial blood pressure showed a rise in both group and it was not statistically significant. In Group S there was rise in mean arterial blood pressure from intubation till end of surgery with maximum increase at end 75, 90 min (9.9%). In Group D there was rise in mean arterial blood pressure from intubation till 60 min with maximum increase at end 15 min (6.1%). In Group D there was fall in mean arterial blood pressure from 45 minutes till end of surgery. Intraoperative cardiovascular stability was easily achieved with both sevoflurane and desflurane. Mean arterial blood pressure and heart rate were maintained within ± 20% of baseline values in both groups during the entire maintenance period. Early recovery profile was rapid in desflurane group. Sevoflurane and Desflurane provided similar intra-operative haemodynamics during the maintenance period in laparoscopic surgery. Early recovery is faster with desflurane.
sevoflurane, desflurane, laparoscopic surgery, recovery