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J App Pharm Sci. 2015; 5(Supplement 1): 061-064

Acute Toxicity Studies and Evaluation of Analgesic Property of the Methanol Stem Bark Extract of Neocarya macrophylla

A. J. Yusuf, M. I. Abdullahi, A. K. Haruna, A. M. Musa, Z. Y. Y. Ibrahim, A. Uba.

The methanol stem bark extract of Neocarya macrophylla was screened for its analgesic activity using acetic acid-induced writhing in mice and formalin-induced pain in rats. The results of the study showed that the extract (60mg/kg, i.p.) decreased writhing response with 63.9% inhibition. The methanol extract also exhibited significant analgesic effect (P

Key words: Neocarya macrophylla, extract, formalin, acetic acid and analgesic models

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