Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

1

IJHSR. 2015; 5(4): 65-72


Prevalence of Hepatitis E Virus among Hemodialysis Patients: One Egyptian Center Study.

Maysaa El Sayed Zaki, Mostafa Abdelsalam, Nahla Hamed Anbar, Basem Salama El-deek.

Abstract
Background: In Egypt Hepatitis E virus (HEV) is considered as an endemic infection.
The aim of the present study was to determine the prevalence of HEV infection among HD patients and to study the risk factors associated with such infection.
Methods: The study included ninety six cohort HD patients in Mansoura University Hospital, Egypt in addition to one hundred sixty seven healthy blood donors. Full virological markers assay for hepatitis B, C and E viruses were performed. Positive samples for serological markers for hepatitis E were subjected to nested PCR for HEV.
Results: HCV IgG was the predominant serological markers among HD (42.7%) followed by HEV IgG (22.9%). Serological virological markers for HCV and HEV were significantly higher in HD patients compared to healthy blood donors (18.6%-5.9%, P=0. 0001, P=0. 02 respectively). HEV viremia was detected in statistically significantly higher percent of HD patients (36.4%) compared to blood donors (20%), P=0. 07.
The duration of dialysis and the number of blood transfusion units had no statistically significant association with HEV viremia. HCV antibodies were prevalent among 50% of patients with HEV viremia.
Conclusion: From this study we can reason that HEV is common infection among hemodialysis patients. Further studies are obliged to clear up the wellspring of HEV disease in dialysis units in Egypt.

Key words: Hemodialysis, HEV, PCR



Share this Article


Advertisement
American Journal of Diagnostic Imaging

SUBMIT YOUR ARTICLE NOW


ScopeMed.com
ScopeMed Home
Follow ScopeMed on Twitter
BiblioCAM
Author Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Suggest a Journal
Publisher Login
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.
Scopemed Buttons