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Egypt. J. Exp. Biol. (Zoo.). 2014; 10(2): 137-143


ROLE OF ERUCA SATIVA OIL TREATMENT ON PROFENOFOS SUPPLEMENTED FEMALE ALBINO RATS

Diaa Farrag Ibrahim Ahmed.

Abstract
Profenofos is one of the organophosphorus insecticides that cause harmful effects on kidneys, liver direct bilirubin, and RBCs. Farmers are the first wall that reacts with profenofos. Eruca sativa (E. s.) oil contains many antioxidants and was considered as the cheapest source for farmers to ameliorate the deleterious effects of profenofos. The aim of the present study is to use a cheap antioxidant material for a short time to ameliorate the harmful effects of the profenofos. The results show significant increases in direct bilirubin in both profenofos and E. s. oil + profenofos groups. Also, there is a significant increase in uric acid in profenofos group. In the addition, there is significant increase in haemoglobin concentration in E. s. oil group. On the other hand, there is significant decrease in urea in E. s. and Oil + profenofos group. Also, uric acid shows significant decreases in both E. s. oil and E. s. oil + profenofos groups. In addition, there is a significant decrease in RBCs count in both profenofos and E. s. oil + profenofos groups. The present work concludes that E. s. oil ameliorates kidney function and haemoglobin through short time of treatment.

Key words: Eruca sativa oil, Profenofos, Liver, Kidney, Haematology



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