Gangliogliomas are rare tumors of central nervous system accounting to 0.4% of total CNS tumors. Gangliogliomas are more common in temporal lobe (85%).We present three cases of ganglioglioma of CNS. Case 1: A 52-year -old Female presented right thalamic tumor operated by microneurosurgical technique through transcollosal approach and diagnosed as thalamic ganglioglioma, grade I on histopathology. Case 2:A 45 –year- female with history of seizures operated by microneurosurgical technique through right temporal craniotomy and diagnosed as right temporal lobe ganglioma grade I. Case 3 : 9-year- old female child presented with headache, neckpain, vomiting and left posterior parieto-occipital transcortical craniotomy and diagnosed as thalamic ganglioglioma grade III. Immunohistochemical stains were performed to confirm the same, which were GFAP,CD34,Synaptophysin,S-100 and MIB-1,Ki-67.
Ganglioglioma, CNS, Microsurgery, Immunohistochemistry