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IJHSR. 2015; 5(6): 720-725


Ganglioglioma of Central Nervous System-Study of 3 Cases-With Review of Literature.

Meghana Chougule, Veerendrasinh Pawar, Rahul Chivate.

Abstract
Gangliogliomas are rare tumors of central nervous system accounting to 0.4% of total CNS tumors. Gangliogliomas are more common in temporal lobe (85%).We present three cases of ganglioglioma of CNS. Case 1: A 52-year -old Female presented right thalamic tumor operated by microneurosurgical technique through transcollosal approach and diagnosed as thalamic ganglioglioma, grade I on histopathology. Case 2:A 45 –year- female with history of seizures operated by microneurosurgical technique through right temporal craniotomy and diagnosed as right temporal lobe ganglioma grade I. Case 3 : 9-year- old female child presented with headache, neckpain, vomiting and left posterior parieto-occipital transcortical craniotomy and diagnosed as thalamic ganglioglioma grade III. Immunohistochemical stains were performed to confirm the same, which were GFAP,CD34,Synaptophysin,S-100 and MIB-1,Ki-67.

Key words: Ganglioglioma, CNS, Microsurgery, Immunohistochemistry



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