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23

BTDMJB. 2016; 12(3): 124-128


Relationship between desease activity and ultrasonographic enthesitis assessment of lower extremity in ankylosing spondylitis

Sibel Çağlar Okur, Özer Burnaz, Yasemin Pekin Doğan, Levent Özgönenel, Nezihe Akar, Ebru Aytekin, Nil Sayıner Çağlar.

Abstract
Objective: We aimed to investigate the relationship between clinical and laboratory indicators of disease activity in ankylosing spondylitis (AS) and Glasgow Ultrasound Enthesitis Scoring System (GUESS) score which is created for diagnosis and monitoring of enthesitis.
Materials and Methods: 50 patients with diagnosis of AS who were following-up in Physical Medicine and Rehabilitation Clinic of Istanbul Training and Research Hospital were included in the study. Routine biochemical tests, complete blood count, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) were analysed. BASDAI, ASDAS-ESR and ASDAS-CRP scores were calculated for desease activity. Clinical enthesitis scores was calculated according to Maastricht Ankylosing Spondylitis Enthesitis Index (MASES). The relationship between clinical and laboratory findings and GUESS scores were investigated.
Results: 37 (74%) male, 13 (26%) female patients were evaluated. Mean disease onset age was 28.2, mean disease duration was 7.18 years. Mean GUESS score was calculated as 11.36 (SD: 5.27). There were not any significant correlation between GUESS scores and age or disease onset age. GUESS scores were slightly significant positively correlated with disease duration (r=0.49 p

Key words: Enthesitis, scoring, ultrasonography



Ankilozan spondilitte hastalık aktivitesi ile alt ekstremite ultrasonografik entezit değerlendiriminin ilişkisi

Özet
Amaç: Ankilozan spondilitte (AS) hastalık aktivitesinin klinik ve laboratuvar göstergeleri ile entezit tanısı ve izlemi açısından USG için geliştirilmiş Glasgow Ultrasound Enthesitis Scoring System (GUESS) entezit skorunun ilişkisini ortaya koymak amaçlandı.
Gereç ve Yöntem: İstanbul Eğitim ve Araştırma Hastanesi Fiziksel Tıp ve Rehabilitasyon Kliniğinde takipli 50 AS hastası alındı. Rutin biyokimya, kan sayımı, eritrosit sedimentasyon hızı (ESR) ve C-reaktif protein (CRP) tetkikleri yapıldı. Hastalık aktivitesi için BASDAI, ASDAS-ESR ve ASDAS-CRP skorları hesaplandı. Maastricht Ankylosing Spondylitis Enthesitis Index (MASES) ile klinik entezit skorları hesaplandı. GUESS yöntemine göre ultrasonografik entezit değerlendirimi yapıldı. Hastaların klinik ve laboratuar bulguları ile GUESS skorları arasındaki ilişki analiz edildi.
Bulgular: Hastaların 37’si (%74) erkek, 13’ü (%26) kadındı. Hastalık başlangıç yaşı ortalama 28.2, ortalama hastalık süresi 7.18 idi. GUESS skoru ortalaması 11.36 (SD: 5.27) olarak hesaplandı. GUESS skoru ile yaş ve hastalık başlama yaşı arasında anlamlı bir korelasyon saptanmadı. GUESS değerleri ile hastalık süresi arasında zayıf derecede anlamlı pozitif korelasyon bulundu (r=0.49 p

Anahtar Kelimeler: Entezit, skorlama, ultrasonografi



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