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PHARMACOGNOSTICAL AND PHARMACEUTICAL STUDIES ON KASAHARA DASHEMANI VATI

NAYAN KUMAR S, KALPANA S PATEL, HARISHA CR, SHUKLA VJ, RAJAGOPALA S.

Abstract
Background: In the present era of geometrical rise of demand for indigenous
medicines, maintaining quality standards is the need of hour. Absence of reference standards for
compound formulations is a hindrance on the way towards standardisation. Objectives: The present
study is aimed at setting a preliminary pharmacognostical and pharmaceutical profile of Kasahara
Dashemani Vati (KD tablet). Methods: Study included preparation of KD tablets using pre
authenticated raw drugs following all SOPs. Later KD tablet was subjected to pharmacognostical,
physicochemical and phytochemical analysis as per standard protocols. The final observations were
systematically recorded. Results: Pharmacognostical findings matched with that of individual raw
drugs negating any major change in the microscopic structure of the raw drugs during the pharmaceutical
processes of preparation of tablet. Tested physicochemical parameters were within the optimum
reference range for a tablet. Phytochemical components such as phytosterols, glycosides, flavonoids
and tannins were tested positive. HPTLC gave a preliminary fingerprint of the formulation with
6, 5 and 5 spots on short UV, long UV and visible spectrum of light respectively. Conclusions:
KD tablet can be screened pharmacognostically for the structures of individual raw drugs to
authenticate the ingredients. It is inferred that the formulation meets the required qualitative
standards at a preliminary level. Identified phytochemicals support intended actions of the formulation
in respiratory system. Thus the quality of KD tablet can be ascertained by pharmacognostical,
physicochemical and phytochemical screening for the findings in accordance with the observations
in present study. The results of this study may be used as the reference in further research
undertakings of its kind.

Key words: Kasahara Dashemani Vati, Pharmacognosy, Chromatography, Standardization.



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