Objectives: We studied the incidence, clinical significance and predictors of transient acute kidney injury in patients undergoing coronary artery bypass graft surgery.
Methods: Eight hundred and sixteen consecutive and isolated CABG patients in a single institution between January 2013 and April 2014 were retrospectively analyzed. The patients were divided into 2 groups: Acute kidney injury group (transient at follow up postoperatively) and non-acute kidney injury group (normal kidney functions). Transient injury was defined as serum creatinine level > 25% of baseline on the1st, 4th or 30th postoperative days.
Results: The percentage of transient injury was 31.7%. In a logistic regression analysis, age (p=0.0001), female sex (p=0.0001) and prolonged mechanical ventilation (p=0.018) were found to be independently associated with development of acute injury after surgery. Most of patients with acute injury had prerenal azotemia after discharge.
Conclusions: Our study showed that fluctuations in kidney functions during 30 day of post-CABG are strongly related to age, female sex and prolonged mechanical ventilation. Besides, some patient-related factors are preventable such as hypovolemia after discharge.
Acute kidney injury; coronary artery bypass; postoperative complications