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Journal-CVS. 2015; 3(3): 54-60


The incidence and predictors of transient acute kidney injury in patients with preoperative normal kidney functions undergoing coronary artery bypass graft surgery

Mehmet Kaya, Mugısha Kyaruzi, Salih Güler, Ihsan Bakır, Mehmet Yeniterzi.

Abstract
Objectives: We studied the incidence, clinical significance and predictors of transient acute kidney injury in patients undergoing coronary artery bypass graft surgery.
Methods: Eight hundred and sixteen consecutive and isolated CABG patients in a single institution between January 2013 and April 2014 were retrospectively analyzed. The patients were divided into 2 groups: Acute kidney injury group (transient at follow up postoperatively) and non-acute kidney injury group (normal kidney functions). Transient injury was defined as serum creatinine level > 25% of baseline on the1st, 4th or 30th postoperative days.
Results: The percentage of transient injury was 31.7%. In a logistic regression analysis, age (p=0.0001), female sex (p=0.0001) and prolonged mechanical ventilation (p=0.018) were found to be independently associated with development of acute injury after surgery. Most of patients with acute injury had prerenal azotemia after discharge.
Conclusions: Our study showed that fluctuations in kidney functions during 30 day of post-CABG are strongly related to age, female sex and prolonged mechanical ventilation. Besides, some patient-related factors are preventable such as hypovolemia after discharge.

Key words: Acute kidney injury; coronary artery bypass; postoperative complications



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