Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

Original Research



Is Further Examination Necessary in Patients with Behçet's Disease Without Any Neurological Signs or Symptoms?

Halit YAŞAR, Mehmet Güney ŞENOL, Semih ALAY, Yalçın ÖNEM, Emine Ece BOYLU, Rıfat Erdem TOGROL, hAKAN TEKELİ, Mehmet SARAÇOĞLU.

Abstract
Background and Purpose: A mean percentage of 5% was reported for neurological involvement in researches related to Behçet's disease. The neurological involvement may be characterized by headache, neuropsychiatric symptoms, brain stem involvement, cerebral venous thrombosis or peripheral nervous system involvement. Sometimes neurological involvement may be seen without any neurological sign or symptom. In our study, we aimed to evaluate the cognitive, psychiatric and neurophysiological responses in Behçet's disease without neurological sign and symptom.
Methods: The study was performed on patients with Behçet's disease without neurological signs and symptoms and healthy volunteers that would make the control group. The patients were assessed with Mini Mental State Examination, Hamilton Rating Scale for Depression, nerve conduction study and visually evoked potential.
Results: A total of 27 male patients (age: 24.88±5.45 years) were enrolled in the study. Neurological examinations of all the patients were normal. Mean Mini Mental State Examination score of the patients was 29.62±0.79 (2 patients had loss of focus, 2 patients had disturbance in the copying function) and 2 patients had mild depression in Hamilton Rating Scale for Depression. In the nerve conduction study, 2 patients had right sensory-motor carpal tunnel syndrome, 1 patient had right sensory-motor carpal tunnel syndrome - bilateral ulnar nerve entrapment. In the visually evoked potential examination, 8 patients had prolonged P100 latency, decreased amplitude and disturbance of wave morphology.
Conclusion: Visually evoked potential examination may be used as a conductive method to detect the subclinical neurological pathologies in Behçet's disease. The possible silent neurological involvement should be evaluated with further neuro-screening methods.

Key words: Behçet's disease, neurological involvement, visually evoked potential (VEP), cognitive, depression, nerve conduction study (NCS)



Share this Article


Advertisement
Journal of Environmental and Occupational Science

SUBMIT YOUR ARTICLE NOW


ScopeMed.com
ScopeMed Home
Follow ScopeMed on Twitter
BiblioCAM
Author Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.
Scopemed Buttons