Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

1

Nig. J. Basic Appl. Sci.. 2015; 23(1): 15-22


Isolation and Characterization of Stigmasterol and Bis-(5, 7-diacetyl-catechin-4-α-rhamnopyranoside) from the Stem bark of Neocarya macrophylla (Sabine) Prance (Chrysobalanaceae)

A.J. Yusuf, M.I. Abdullahi, A.K. Haruna, A.Y. Idris and A.M. Musa.

Abstract
Neocarya macrophylla belongs to the Chrysobalanaceae family and is extensively used in folk medicine as an antibacterial, antivenin, antiasthmatic, anticancer, analgesic and anti-inflammatory agent. This study was aimed at isolation and characterization of compounds from the stem bark of Neocarya macrophylla. Pulverized plant material was exhaustively extracted with methanol using maceration method and concentrated in-vacuo with the aid of rotary evaporator at 40oC to afford a reddish brown crude methanol extract (ME). The methanol extract was successively partitioned into hexane, dichloromethane, ethylacetate, n-butanol and aqueous fractions. Stigmasterol was isolated from the hexane fraction and a catechin glycoside, Bis-(5,7-diacetyl-catechin-4-α- rhamnopyranoside) was isolated from the ethylacetate soluble fraction using a combination of silica gel column, gel filtration (sephadex LH-20) and preparative thin layer chromatography. The structures of the compounds were established on the basis of chemical tests, spectroscopic analysis and by comparison with reference spectral data.

Key words: Neocarya macrophylla, phytochemical, stigmasterol, Bis-(5, 7-diacetyl-catechin-4-α-rhamnopyranoside).



Share this Article


Advertisement
American Journal of Research in Medical Sciences

SUBMIT YOUR ARTICLE NOW


ScopeMed.com
ScopeMed Home
Follow ScopeMed on Twitter
BiblioCAM
Author Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Suggest a Journal
Publisher Login
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.
Scopemed Buttons