Introduction: Bone marrow (BM) involvement by lymphoma is considered a systemic dissemination of disease elsewhere, although some tumors may arise primarily in the BM microenvironment. Primary Bone Marrow Lymphoma (PBML) is a rare entity whose real boundaries, treatment and clinico-biological significant aren’t well defined. Case report: Here we present a case of 61 year old female, who was diagnosed with PBML. She achieved remission after 8 cycles of chemotherapy. Unfortunately, the patient relapsed after 6 months of remission. Conclusion: PBML is an uncommon lymphoma with unfavorable outcome. Its recognition is essential for accurate diagnosis and adequate therapeutic strategy.
bone marrow, Non Hodgkin’s lymphoma (NHL), Primary lymphoma