Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

2



Genetic and Environmental Contributions to Human Longevity

Awoyemi Abayomi Awofala, Olusegun Emmanuel Ogundele.

Abstract
Human longevity, like most complex phenotypes, is thought to reflect a complex interplay of both environmental (e.g. lifestyle choices, where we live in) and genetic factors. These factors are likely to influence the basic mechanism of ageing and in turn broadly influence susceptibility to age-related illness. Thus, good lifestyle choices and conducive environment coupled with lack of genetic variants that predispose to diseases as well as having variants that confer resistance to diseases are probably vital to achieving old age. Although, the scientific understanding of the mechanism governing longevity is still sparse, understanding its biological underpinnings, including the potential contribution of genes and environment, is a key for shaping individualís lifestyle choices and developing efficacious therapeutic targets to increase lifespan. This review provides an overview of different strategies that are being integrated increasingly to extend our knowledge of the genetic and environmental underpinnings of human longevity.

Key words: Human longevity, genes, environment, epigenetics, linkage analysis association studies, gene-environment interaction



Share this Article


Advertisement
Journal of Behavioral Health

SUBMIT YOUR ARTICLE NOW


ScopeMed.com
ScopeMed Home
Follow ScopeMed on Twitter
BiblioCAM
Author Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Suggest a Journal
Publisher Login
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMedģ Information Services.
Scopemed Buttons