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IJHSR. 2015; 5(10): 65-72


Role of Oral Gadolinium as a Negative Contrast Medium in Magnetic Resonance Cholangiopancreatography.

Aparna S. Bhatwal, Abhijit M. Patil, Abhimanyu B. Kelkar, Rushikesh A. Naik.

Abstract
In our study, we aimed to evaluate the efficacy of the use of a negative oral contrast agent such as gadolinium - Gd-DOTA (gadolinium-tetraazacyclododecane-tetraacetic acid-meglumine) in MRCP (Magnetic Resonance Cholangiopancreatography) for proper visualisation of the hepatobiliary tree and pancreatic duct. The fluid-filled stomach and duodenum often cause obscuration of the hepatobiliary tree and pancreatic duct. Forty-one consecutive patients, who were referred for MRCP with a clinical suspicion of pancreaticobiliary duct disease, were prospectively examined before and immediately after ingestion of a Gd-DOTA 0.5 mmol/ml solution (1 ml Gd-DOTA). The images obtained before and after the intake of a negative oral contrast agent were studied and compared. We found herein that the contrast agent Gd-DOTA (gadolinium-tetraazacyclododecane-tetraacetic acid-meglumine) constitutes an efficient negative oral contrast agent for MRCP, for it efficiently eliminates the signal of the digestive tube in MRCP images.

Key words: oral gadolinium, negative oral contrast, MRCP, pancreatobiliary system.



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