OBJECTIVES: This study was carried out to compare the placentae from hypertension associated
pregnancies and normal pregnancies
DESIGN: Comparative study
SETTING: Isra University Hospital Hyderabad Sind.
METHOD: Eighty full term placentae were collected; 40 from normal and 40 from hypertensive
pregnant women. Gross features of placentae were noted and then stained for their microscopic
features. Birth weight and Apgar score of the newborn were recorded.
RESULTS: The weight and surface areas of placentae were significantly low in the hypertensive
group whereas thickness of placenta and number of cotyledons were almost same in hypertensive
and control groups. Microscopically increased number of syncytial knots, chorionic villi
with excessive collagen was observed in placentae of hypertensive women. In hypertensive
group birth weight of neonates was significantly low than control group while difference in APGAR
score between two groups was statistically insignificant.
CONCLUSION: Hypertension during pregnancy is associated with remarkable changes in the
Placenta, APGAR score, hypertensive, normotensive, birth weight.