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Thyroid function in hypertensives in South-South Nigeria

Iya E. Bassey, Rebecca M. Gali, Okon E. Essien, Alphonsus E. Udoh, Bukola Emordi, Uwem O. Akpan.

Background: Hypertension is the most common cardiovascular disease afflicting humans. It has been reported that hypertensive patients may have a tendency for impaired thyroid function but, these results have not always been confirmed. The aim of this study therefore was to determine the serum level of thyroid hormones in hypertensive subjects and any possible relationship between serum thyroid hormone levels and hypertension.
Methods: Blood samples were consecutively obtained from One hundred and seventy (170) consenting subjects. One hundred were hypertensive subjects while seventy subjects were normotensive controls. Triiodothyronine (T3), Thyroxine (T4) and Thyroid stimulating hormone (TSH) were analyzed using ELISA kits. Data was analyzed using student t test and analysis of variance. The difference was considered statistically significant at p < 0.05.
Results: The mean serum TSH value for hypertensive subjects was 3.012.42 Iu/ml and was significantly higher (p

Key words: Thyroid hormones, Hypertension, Subclinical hypothyroidism

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