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Tolosa Hunt syndrome: a rare syndrome

Spandan Patel, Prachi Sankhe, Dhaval Dave, Smita Patil, Manish Pendse.

Tolosa Hunt Syndrome (THS) is rare syndrome with an estimated annual incidence of 1 case per million per year. THS is painful ophthalmoplegia caused by nonspecific inflammation of cavernous sinus or superior orbital fissure. It is often unilateral with severe headache and ophthalmoplegia involving third, fourth, fifth and sixth cranial nerves. We present a case admitted in our hospital that came with complaint of severe unilateral headache with loss of vision of left eye. He did not have any other significant history except that he was complaining of partial sensory loss over left upper part of face. Ophthalmologist reference was taken to rule out any other cause involving optic disc and funduscopy which was normal. Further investigations were done which ruled out all possible causes. Patient was started on steroids and on MRI scan and clinical presentation, patient was diagnosed as Tolosa- Hunt Syndrome. Thus we report a rare case of THS which showed gradual recovery with corticosteroids.

Key words: Tolosa Hunt Syndrome, Granulomatous inflammation, Cavernous sinus, Superior orbital fissure

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Journal of Molecular Pathophysiology


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