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IJHSR. 2015; 5(12): 460-464


Leiomyosarcoma of the Dermis- A Rare Presentation with a History of Recurrence.

S. Shifa Ibrahim, G.Meena kumara, N. Sharmila Thilagavthy, C.Sofia Tamilarasi.

Abstract
Cutaneous Leiomyosarcoma is a rare tumor with an incidence of 2-3% of all the superficial smooth muscle tumors. Cutaneous leiomyosarcoma is divided based on the prognosis into leiomyosarcoma arising from the dermis and subcutaneous plane. Metastasis, recurrence and death are more common in subcutaneous leiomyosarcoma when compared with dermal LMS. Dermal leiomyosarcoma is a tumor of an adult with a male preponderance with a peak age incidence of 60 years. Commonest site is the extremities. These tumors are usually smaller in size. Histopathologically, two growth patterns are recognized, diffuse and nodular. Atypia and mitosis more than one per 10 high power fields are the diagnostic criteria that help in distinguishing cutaneous leiomyosarcoma from leiomyoma. Markers like smooth muscle actin and caldesmon are helpful in arriving at the diagnosis. Treatment is wide local excision with 2-5cm margin. The depth, size, location and grade alter the prognosis.

Key words: Subcutis, Extremities, Smooth muscle actin.



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