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JARMS. 2014; 6(3): 209-212


ANTIBIOTIC RESISTANCE PATTERN IN E.COLI CAUSING COMMUNITY- ACQUIRED URINARY TRACT INFECTIONS

*Anand Nitika, Asthana Ashish K., Madan Molly, Vats Alka Dixit.

Abstract
Introduction: Urinary tract infections are one of the most prevalent infections both in the community and hospital settings. E.coli has emerged as the most common cause of community acquired urinary tract infections(CA-UTI).Study of its antibiotic resistance profile is pertinent for appropriate treatment. This study was conducted to evaluate antimicrobial pattern amongst E.coli isolates causing community acquired urinary tract infections at a tertiary care hospital in Meerut. Methodology: A total of 967 consecutive urine samples were cultured over a period of six months. E.coli was isolated using conventional methods. Antibiotic susceptibility testing by Kirby-Bauer disk diffusion method was done for ciprofloxacin, amikacin, ampicillin/sulbactam ampicillin, nitrofurantoin, co-trimoxazole, imipenem,meropenem. Result: Of the 116 positive urine samples, 71 showed growth of E.coli.Furthermore, 35.2% of E.coli were ESBL producers.Antibiotic susceptibility of E.coli showed that 85.9% were susceptible to amikacin, 18.3% to ampicillin, 30.9% to co-trimoxazole, 47.8% to ampicillin/sulbactam, 92.9% to nitrofurantoin, 32.39% to ciprofloxacin,74.6% to meropenem and 100% to imipenem.

Key words: CA-UTI, antibiotic susceptibility,ESBL.



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