Objectives: There is an ongoing debate regarding the clinical term “Pregnancy Tumor”- whether it should be used or not. Based on its clinical appearance and histological findings, few investigators consider it to be just a representation of pyogenic granuloma, whereas others believe it to be a distinct lesion due to the influence of female sex hormones. To explicate this issue, a study was undertaken to determine whether a significant correlation exists between pregnancy tumor and pyogenic granuloma.
Materials and Methods: 18 cases that were clinically diagnosed as pregnancy tumors and 20 cases of pyogenic granulomas of non-pregnant individuals were selected as study group and control group respectively. All the clinical presentation and routine H & E stained histopathology of both the groups were studied.
Results: The results indicated that there is a progressive increase in the incidence of pregnancy tumor as the gestation period proceeds and also there is significant similarity between pregnancy tumor and pyogenic granuloma of young non-pregnant females and significant difference between pregnancy tumor and pyogenic granuloma of males and elderly non-pregnant females.
Conclusion: The study supports the concept that pregnancy tumor should be separated from pyogenic granuloma and should be considered as a distinct lesion. It also suggests the role of female hormones in the development of the lesion.
pregnancy tumor, pyogenic granuloma.