Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

23

Natl J Integr Res Med. 2016; 7(1): 59-66


To Establish The Involvement Of Central Dopaminergic And Serotonergic Mechanism Of Ginger-Juice On Amphetamine And Lithium Treated Rat

S.S.Prasad*, Chaitali Shah**, Anupama Desai**, S.K.Vajpeyee***, V.H. Bhavsar***.

Abstract
Background & Objective: To establish the involvement of central dopaminergic and serotonergic mechanismof ginger-juice (ZINGIBER OFFICINALE ROSCOE) CNS parameters in rat. Methodology: (A) Albino rats (n=6-12) were administered G.J at two doses (2ml & 4 ml/rat, p.o) as single administration and chronic treatment over period of 30 days. Following this assessment was done. Effect of treatment with G.J acutely and chronically (30days) administered, was assessed. Parameters used during assessment were total acidity, gastric volume & pH and ulcer index ‘UI’(acute and chronic). Results & Conclusion: Ginger administered itself did not affect loco motor activity as well as amphetamine-induced enhancement of loco motor activity.Lithium induced head twitches were enhanced after chronic administration indicating enhanced serotonergic system in the central nervous system. [Prasad S NJIRM 2016; 7(1):59-66]

Key words: Ginger-juice, Amphetamine,Lithium, Locomotor, static activity, analgesic.



Share this Article


Advertisement
Journal of Behavioral Health

SUBMIT YOUR ARTICLE NOW


ScopeMed.com
ScopeMed Home
Follow ScopeMed on Twitter
BiblioCAM
Author Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Suggest a Journal
Publisher Login
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.
Scopemed Buttons