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Comparison of the efficacies of normal saline versus hypertonic saline in the management of acute bronchiolitis’

Oya Koker, Sebnem Ozdogan, Gulsen Kose, Zeynep Y. Yildirmak.

Abstract
Background: The aim of this study was to compare the efficacies of saline solutions of different concentrations used for the management of infants with mild to moderate bronchiolitis.
Methods: A retrospective chart review of 46 children, aged 1-24 months, diagnosed with acute bronchiolitis was performed. The patients were separated into 2 groups: normal saline and 3% hypertonic saline. Length of hospital stay, modified respiratory assessment score (MRAS) at admission, at 48 hours of admission and at discharge were compared.
Results: MRAS evaluated at admission, at 48 hours after admission and at discharge and length of hospital stay did not reveal significant difference between the two groups (p>0.05).
Conclusions: Comparison of two different treatments, salbutamol applied in combination with either normal saline or 3% hypertonic saline, did not reveal any statistically significant differences with respect to symptomatic improvement or length of hospital stay.

Key words: Bronchiolitis, Hypertonic saline solution, Respiratory syncytial virus



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