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Plasmablastic Lymphoma: A Report of 2 Cases with Review of Literature.

Geetha Vasudevan, Brij Mohan Kumar Singh, Arijit Bishnu, Abhijat Kulshreshta.

Abstract
Plasmablastic lymphoma (PBL) is an aggressive subtype of Non-Hodgkin Lymphoma (NHL) initially described in extra-nodal sites in an immunocompromised and later in immune-competent patients. PBL remains a diagnostic challenge due to morphological overlap with various other entities and also due to similarities on immunohistochemistry with plasma cell myeloma. In-spite of therapeutic advances, PBL remains an aggressive disease with high fatality rate. We describe 2 cases of this uncommon neoplasm; both in immunocompromised patients.

Key words: Non-Hodgkin Lymphoma, Immunocompromised, Immunohistochemistry



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