Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access


Pulmonary metastasis in laryngeal squamous cell carcinoma

Gülpembe Bozkurt, Meltem Esen Akpınar, Didem Rıfkı, Senem Kurt Dizdar, Uğur Temel, Berna Uslu Coşkun.

Objective: To identify the factors associated with pulmonary metastasis, such as lymph node positivity, tumour location and histological differentiation in patients with laryngeal squamous cell carcinoma (scc).
Material and Methods: This study is designed as retrospective cohort study. Data from 263 patients diagnosed with laryngeal scc were reviewed retrospectively. Pulmonary metastasis was observed in 39 of these patients.
Results: The transglottic tumors had the highest pulmonary metastasis rate (%50). The pulmonary metastasis rate was significantly lower in patients with glottic tumors than those with tumors in other regions (p= 0.003) The pulmonary metastasis rate was higher in lymph node-positive patients than in lymph node-negative patients. Pulmonary metastasis rate was significantly higher among patients with N2-N3 stage lymph nodes compared to those with N1 stage lymph nodes. Pulmonary metastasis rate is also increased significantly among patients with histologically poorly differentiated tumors (p= 0.001).
Conclusion: The laryngeal cancer patients with positive lymph node, with transglottic tumour and with poorly/moderately differentiated tumour should be monitored carefully and followed up closely for possible pulmonary metastasis.

Key words: Larynx carcinoma, lymph node, pulmonary metastasis

Share this Article

Journal of Molecular Pathophysiology


ScopeMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.
Scopemed Buttons