Background: To compare efficacy of Gallium nitride derived light-emitting diodes (LED) phototherapy with special blue compact fluorescent lamp (CFL) phototherapy in management of neonatal hyperbilirubinemia in terms of rate of fall of serum bilirubin levels, required duration of phototherapy and to compare the incidences of clinically observable side effects between both groups.
Methods: A randomized prospective observational study was carried out at tertiary level of neonatal intensive care unit over a period of one year. Stable neonates of gestation >34 weeks with hyperbilirubinemia requiring phototherapy, were included. Sick babies, Rh iso-immunized babies, those who required and underwent exchange transfusion and whose parents refused for consent were excluded. Babies were enrolled on consecutive basis and after randomization were allocated to receive phototherapy by LED or CFL. CFL and LED were both special blue lights with irradiance maintained above 15 µW/nm/cm2. Vital parameters and clinically observable side effect were recorded 12 hourly till phototherapy was stopped.
Results: 100 babies were enrolled in each group. Baseline characteristics, causes of jaundice, baseline haemoglobin and TSB were similar in both groups. Base line irradiance was more in LED group compare to CFL group (P=0.0006, highly significant). Rate of fall of serum bilirubin (p 0.05).
Conclusions: LED phototherapy is superior to CFL phototherapy in management of neonatal hyperbilirubinemia in terms of efficacy and side effects.
Jaundice, Neonate, Phototherapy, Hyperbilirubinemia