PAFMJ. 2016; 66(3): 346-350
ROLE OF SUBMUCOSAL TRAMADOL IN PAIN CONTROL AFTER MANDIBULAR THIRD MOLAR SURGERYMuhammad Nazir khan, Muhammad Wajahat Ghafoor, Muhammad Jahanzaib, Qasim Nafees Ahmad, Minal Masood, Qalab Abbas.
Objective: The objective of this study was to find the analgesic effects of sub mucosal tramadol after 3rdmolar extraction.
Study Design: Study design was randomized, double-blind and placebo-controlled.
Place and Duration of Study: The study was conducted in Armed Forces Institute of Dentistry, Rawalpindi for a period of 4 months from 23rd February 2015 up till 30th June 2015.
Material and Methods: Sixty patients underwent third molar extractions (Pell & Gregory class 2, Position B, mesioangular). They were divided into two groups. Surgical site was randomly assigned to sub mucosal 100mg/2ml tramadol injection (group T) or normal saline solution (group P) immediately after surgery. Time of intake and amount of analgesic rescue drug, and postoperative pain intensity were recorded immediately after anesthesia cessation and 4, 8, 24and 48hours after surgery.
Results: Anesthetic blockade duration between groups was similar. In comparison to group P, time elapsed before first intake of rescue drug was longer, and pain intensity was lower significantly in group T (p = 0.000).
Conclusion: The local administration of 100mg/2ml tramadolcontributes to provide a prolonged pain-free period post-operatively and thus helps in controlling the amount of analgesics (specifically NSAIDS) consumed, increase patient comfort and compliance resulting in better quality of life.
Analgesics, Third molar, Tramadol.
American Journal of Physiology, Biochemistry and Pharmacology
SUBMIT YOUR ARTICLE NOW