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Natl J Integr Res Med. 2012; 3(3): 152-155

A Clinical Profile of Oral Submucous Fibrosis

Dr. Mitesh Amitkumar Modi*, Dr. Vishal R. Dave**, Dr. Viral G. Prajapati***, Dr. Keyur A. Mehta****.

Background: Oral submucous fibrosis (OSF) is a precancerous condition associated with the use of areca nut in various forms. There are very few reports to correlate the clinical stage to histopathological grading in OSF. Materials and Methods: A hospital-based study was conducted on 80 oral Submucous Fibrosis cases who visited our hospital in Jamnagar.. A detailed history of each patient was recorded along with a clinical examination. Biopsy was performed for histopathological correlation. Clinical stage of the disease in terms of the ability to open one's mouth was correlated with histopathological grading. Results: The male to female ratio of OSF cases was 3:1. All forms of areca nut products were associated with OSF. Chewing of paanmasala was associated with early presentation of OSF as compared to chewing of the betel nut The the result of all conservative therapy fails to reverse the disease. Conclusion: result of study recommend primary prevention for prevention of OSF [ Modi M et al NJIRM 2012; 3(3) : 152-155]

Key words: Areca nut, clinical staging, histopathological grading, oral submucous fibrosis

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