Abstract: Background: The esthetic quality of a restoration may be as important to the mental health of the patient as the biological and technical qualities of the restoration are to his physical or dental health. In Conservative Dentistry; to mimic, repair and reconstruct the natural tooth structure for the long term, would be based on the use of a restorative material retained only by an adhesive system, whether in load bearing or non-load bearing environments. To achieve high strength, bonds between tooth structure and restorative materials have been a long term goal of dental profession. Aim: The aim of this in vitro study was to compare the shear bond strength of two different dentin bonding agents with two different desensitizers. Materials and Methods: Eighty molars were taken, which were ground to expose dentin. The teeth were divided into two major groups. Each major group was subdivided into four subgroups of 10 samples each. Groups Ia and IIa were treated as dry bonding groups, groups Ib and IIb were treated as moist bonding groups, group Ic and IIc were rewetted with Gluma desensitizer, and groups Id and IId were rewetted with Systemp® desensitizer. Major group I was treated with Gluma comfort bond and Charisma. Major group II was treated with 3M ESPE Adper™ Single Bond 2 and 3M ESPE Filtek™ Z250. The samples were thermocycled and shear bond test was performed using Instron machine. The data was analyzed using one-way analysis of variance and Tukey’s significant different test. Results: The results revealed that the specimens rewetted with Gluma desensitizer showed the higher shear bond strength compared to all other groups, irrespective of the bonding agent or composite resin used. Conclusion: It can be concluded that the moist or rewetting technique could preserve the micro-morphological integrity of the collagen resulting in the optimum penetration of adhesive resin into the demineralized layer, thus, giving higher bond strength. [Dr.Vibha D NJIRM 2016; 7(4): 117-124]
2-hydroxyl ethyl methacrylate, glutaraldehyde, rewetting agents, shear bond strength.