Arterial hypertension is a frequent worldwide health disorder prevalent in a large percentage of the population and has adverse effects on the brain throughout one’s lifespan. This study was undertaken to evaluate the VEP as potential markers of early nervous system damage in essential hypertension and also to correlate the changes if any, between blood pressure and VEP in patients with essential hypertension.
In the present study, 50 patients of primary hypertension were examined along with a group of 50 normotensive individuals as controls. Primary hypertensive individuals, in the age range of 30-70 years were selected from hypertensive clinic and 50 controls selected from amongst the staff of college.
All the subjects of the two groups then underwent VEP assessment test in the neurophysiology laboratory as per the procedure mentioned under the methodology.
Mean values of VEP in the two groups of subjects compared, showed statistically non-significant increase of absolute latencies of VEP waves.
It is concluded that further studies are needed to substantiate these changes, especially in large number of patients in various grades of severity of hypertension. These changes in our group of subjects supports our hypothesis and needs further confirmation in patients with longer duration of disease as well as study of effect of various factors such as age, target organ involvement and anti-hypertensive drugs.
VEP, Primary Hypertension.