Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

2

IJHSR. 2016; 6(9): 443-450


Wilsonís disease: A Review on Clinical Presentation, Diagnostic Methods and Treatment.

Babitha Annie Eapen, Ammu A, Jasmin Elizabeth Thomas, Merin Joseph, Apollo James, T Sivakumar.

Abstract
Wilsonís disease is an inherited disorder characterized by the excessive accumulation of copper or abnormal copper metabolism. It occurs predominantly in the liver and brain. The genetic factor leading to Wilsonís disease is the mutation of copper transporting gene ATP7B.The main clinical symptoms in Wilsonís disease include neurological, psychiatric and hepatic. The primary treatment in Wilsonís disease is use of copper chelating agent such as D-penicillamine and trientine. This review discusses the pathophysiology, etiology, clinical presentation, diagnosis and management of Wilsonís disease.

Key words: Wilsonís disease, Copper, liver, Kayser-Fleischer ring.



Share this Article


Advertisement
American Journal of Physiology, Biochemistry and Pharmacology

SUBMIT YOUR ARTICLE NOW


ScopeMed.com
ScopeMed Home
Follow ScopeMed on Twitter
BiblioCAM
Author Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Suggest a Journal
Publisher Login
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMedģ Information Services.
Scopemed Buttons