Pleomorphic liposarcoma (PLS) is the rarest subtype of liposarcoma. It is an aggressive and fast growing tumor and is commonly located in the deep soft tissues of the lower and upper extremities. The typical age of presentation is 50-70 years. The incidence is approximately 1 in 2,000,000 per year and accounts for 5-10% of all liposarcoma cases. Herein we are reporting a case of pleomorphic sarcoma in a 60 years old male who was clinically diagnosed with carcinoma rectum. This case is being reported in view of its rarity and mimicking clinically as carcinoma rectum.
Pleomorphic liposarcoma, Rectum, S-100, Vimentin.