Frequency of Depression in Patients Undergoing Coronary Artery
Bypass Grafting Surgery (CABGS), Before the Surgery, at Discharge
and at Six Months Follow upMuhammad Iqbal Afridi, Sultana Habib, Chooni Lal, Arif ur Rehman Khan,
Syed Muhammad Afaq, Qazi Daniyal Tariq.
INTRODUCTION: Depression is much frequent in patients undergoing CABGS. However,
severity was reduced post operatively. Counseling and psychosocial interventions can play an
important role in recovery and functionality of patients.
OBJECTIVE: To compare the frequency of depression in patients undergoing coronary artery
bypass grafting surgery (CABGS) before the surgery, at discharge and at six months follow up.
DESIGN: Prospective, observational study conducted from Dec 2008 to Dec 2009.
SETTING: National Institute of Cardiovascular Diseases (NICVD) Karachi.
METHODS: One hundred and thirty four (134) patients of 18+ years old who were consecutively
listed for first time CABGS were included in the study after fulfilling the inclusion and exclusion
criteria and addressing the ethical issues. ICD-10 criteria to diagnose and Hamilton Rating Scale
for Depression (HAM-D) were applied to assess the frequency and severity of depressive
disorder respectively. Results were analyzed using SPSS version 17.0.
RESULTS: One hundred and thirty four (134) patients undergoing CABGS fulfilled the criteria
for Depressive disorder. One hundred and thirteen (84.3%) were male and 21 (15.7%) were
female with age range 33 to 75 years (mean 53.7 ±SD 8.57). Preoperatively 132 (98.5%)
patients and postoperatively 108 (80.6%) patients were depressed. At 6 months follow up which
was available in 73 patients, only 12 (16.4%) were found depressed. Both genders were almost
equally affected. Surprisingly age, ethnicity, education and co-morbids did not show a
CONCLUSION: Depression is commonly reported before and after cardiac surgery procedures
and it significantly influences the quality of life of the patients undergoing CABGS. The
consequences can increase morbidity and mortality.
Depression, Coronary Artery Bypass Graft Surgery, at discharge, Follow up.
American Journal of Physiology, Biochemistry and Pharmacology
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