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J Liaquat Uni Med Health Sci. 2006; 5(2): 71-75


CLINICO- PATHOLOGICAL PROFILE OF PATIENTS WITH BREAST DISEASES AT UNIVERSITY HOSPITAL, JAMSHORO

K. Altaf H. Talpur, Abdul Aziz Laghari, Arshad Mehmood Malik and Aisha Memon.

Abstract
OBJECTIVES: To assess various disorders of breast regarding their frequency, presentation,
pathology and management at a University Hospital.
DESIGN: A descriptive study.
SETTING: Department of Surgery, Liaquat University Hospital Jamshoro Sindh from January
1999 to December 2003.
PATIENTS AND METHODS: One hundred and fifty patients with different breast disorders were
studied. All cases were assessed clinically by getting history on a predesigned proforma and
diagnosis was confirmed with help of relevant investigations. Patients with various breast diseases
were included in the study except those who were having either no definite lump or no
breast pathology. The treatment given was according to type of lesion in the form of surgery or
conservative. Patients with benign breast diseases were assured and followed up after surgical
treatment or kept on hormone therapy where as cases with malignant disease were referred to
oncologist for cancer registry purpose and chemo-radiotherapy.
RESULTS: Among 150 cases, majority was females with female to male ratio of 24:1. All patients
presented with breast lump (100%), followed by pain in the lump (53.33%) as main symptoms.
Left breast was involved in 53.33% and right breast in 44.66% of cases. Majority of cases
(84.67%) underwent surgery. Histopathology revealed fibro-adenoma in 30.66%, fibrocystic disease
in 15.33% and carcinoma in 35.33% cases as main disorders. All six male patients had gynaecomastia.
CONCLUSION: In our set up, frequency of carcinoma of breast is increasing as compared to
benign lesions. However, overall benign problems are more frequent than breast cancer.

Key words: Breast diseases. Pathology. Malignancy. Surgery.



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