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The pharmacological treatment of psychotic depression

Abdurrahman Altındağ, Mustafa Özkan.

Abstract
Psychotic depression is a severe form of mood disorder characterized
by delusions or hallucinations. Patients with psychotic
depression have a considerably better response rate to the
combination of a tricyclic antidepressant with an antipsychotic
or the combination of serotonin selective reuptake inhibitors
(SSRIs) with an antipsychotic, amoxapine, or electroconvulsive
therapy. The SSRIs alone or atypical antipsychotics alone have
yet to receive any widespread recognition, despite some recent
studies which indicate that they might be recommended as
first-line treatment in psychotic depression. In this paper, the
studies about the pharmacological treatment of psychotic
depression were reviewed.

Key words: psychotic depression, pharmacological treatment, antidepressants, antipsychotics



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