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J. Anim. Sci. Adv.,. 2014; 4(1): 641-647

Evaluation of Growth Performance and Hepatic Histological Changes in Albino Rats Fed Varying Levels of Differently Treated Castor Bean Cake Based Diets

Taiwo Oladoye Akande, Adeyinka Adeniyi Odunsi, Adewale O Emiola, Olusegun S Adedeji.

Forty eight weaned albino rats were used to determine the growth and hepatic histological response of Albino rats fed varying levels of detoxified castor bean cake based diets. There were 12 treatments, with four rats per treatment arranged in a 4 x 3 experimental layout (four processing methods (Boiling, Lye, Roasting and Germination) and three levels of inclusion (0, 5% and 10%). The animals were individually housed in small fabricated cages. Results showed that the processing methods affected the chemical profile of castor bean cake. There was a short fall in energy values of treated castor bean cake compared to raw bean. The crude protein of the lye treated, boiled, and roasted CBC fell while antinutritional factors were better deactivated by boiling and lye treatment. Boiling and lye treatment were able to achieve about 43% and 55% reduction of lectin (ricin) respectively and this was translated in the higher feed consumption and better (P

Key words: albino rats, castor seed, detoxification, performance, histology

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