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Soft neurological signs in children of schizophrenic parents: A controlled study

Osman Önal, Çiğdem Demir, M. Emin Ceylan.

Objective: In this study, we aimed find out the value of the
soft neurological signs in children of schizophrenic parents.

Method: In the study, 8-18 year-old 43 healthy children of
30 schizophrenic parents and 8-18 year old 45 healthy
children of 30 healthy parents were included. Neurologic
Evaluation Scale (NES) was administered to all subjects.

Results: Soft neurological sign severity (intensity) and
frenquency was statistically higher in children of
schizophrenic parents than the control groups' children.

Conclusion: Long-term follow up studies are needed for
evaluation of these results as an indicator of predicting

Key words: soft neurological signs, schizophrenia, high risk study, neurodevelopmental hyphothesis

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American Journal of Physiology, Biochemistry and Pharmacology


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