Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access


An overview of the definition and management of treatment-resistant depression

Diane Bird, Peter M. Haddad, Serdar M. Dursun.

In this article, we review the literature defining treatment-resistant depression and pharmacological strategies to manage these
difficult and challenging clinical cases. Augmentation strategies reviewed in this paper are limited and include the classic and
very well-established antidepressant-augmenters such as lithium and thyroid, in addition to the newer use of pindolol and
tryptophan. We also present possible clinical variables which may be complicating the choice, administration and monitoring
safely and effectively during switching and augmenting antidepressant drugs.

Key words: treatment-resistant depression, depression, pharmacotherapy, psychopharmacology, lithium, thyroid hormones, pindolol, tryptophan, serotonin, ECT

Share this Article

Archives of Clinical and Experimental Surgery (ACES)


ScopeMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Suggest a Journal
Publisher Login
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.
Scopemed Buttons